Pronunciation : iver·mec·tin
Trade Name(s) : IVERMECTOL
Why it is prescribed: It binds selectively and with high affinity to glutamate gated chloride ion channels which occur in invertebrate nerve muscle cells. This leads to increase in permeability of cell membrane to chloride ions with hyperpolarization of nerve or muscle cell, resulting in paralysis and death of parasite.
When it is to be taken: It is administered as a single oral dose therapy. Scabies & strongyloidiasis. 200mg/kg/bw onchocerciasis - 150mg/kg bw.
How it should be taken: The medication comes in the form of 3 & 6mg tablets.
Special Instruction : Hypersensitivity & patients with CNS disorders. Children under 5 years of age or people below 15 kg bw should be taken with water. Need for repeated stool examination to document clearance of infection with strongyloides stercoralis.
Side Effects : Nausea, vomiting, constipation, abdominal pain & fatigue.
Other Precautions : Use with caution in case of pregnancy & lactation.
Storage Conditions : Store at room temperature.
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